Genetic Variation inCYP17A1Is Associated with Arterial Stiffness in Diabetic Subjects
نویسندگان
چکیده
منابع مشابه
Genetic Variation in CYP17A1 Is Associated with Arterial Stiffness in Diabetic Subjects
Hypertension and arterial stiffness are associated with an increasing risk of diabetes and cardiovascular diseases. This study aimed to identify genetic variants affecting hypertension and arterial stiffness in diabetic subjects and to compare genetic associations with hypertension between prediabetic and diabetic subjects. A total of 1,069 participants (326 prediabetic and 743 diabetic subject...
متن کاملArterial Stiffness is Associated With Diabetic Retinopathy in Korean Type 2 Diabetic Patients
OBJECTIVES We evaluated the association between common carotid artery intima-media thickness (CCA-IMT), brachial-ankle pulse wave velocity (baPWV), carotid plaque, and peripheral arterial disease (PAD) as indicators of macroangiopathy and diabetic retinopathy as an indicator of microangiopathy in type 2 diabetic patients. METHODS We analyzed 605 type 2 diabetic patients registered at a public...
متن کاملAssociation of genetic variation on chromosome 9p21.3 and arterial stiffness.
OBJECTIVES Genome wide association studies have consistently reported associations between a region on chromosome 9p21.3 and a broad range of vascular diseases, such as coronary artery disease (CAD), aortic and intracranial aneurysms and type-2 diabetes (T2D). However, clear associations with intermediate phenotypes have not been described so far. To shed light on a possible influence of this c...
متن کاملArterial stiffness is associated with orthostatic hypotension in elderly subjects with history of falls.
OBJECTIVES To test the hypothesis that impaired hemodynamic orthostatic changes commonly observed in the elderly may be related to age-related increase in arterial wall stiffness. DESIGN Convenience sample of consecutive patients admitted for falls. SETTING Acute- and intermediate-care geriatric ward of a French hospital. PARTICIPANTS Fifty-seven elderly patients (46 women) consecutively ...
متن کاملEchogenic carotid plaques are associated with aortic arterial stiffness in subjects with subclinical carotid atherosclerosis.
A better understanding of the interrelationships between the structure and function of the large arteries would lead to optimize cardiovascular disease prevention strategies. In this study, we investigated the relationships of aortic arterial stiffness assessed by carotid-femoral pulse-wave velocity (PWV), with carotid plaque echogenicity assessed by B-mode ultrasound. We analyzed 561 subjects ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Experimental Diabetes Research
سال: 2012
ISSN: 1687-5214,1687-5303
DOI: 10.1155/2012/827172